Training network to advance integrated computational simulations in translational medicine, applied to intervertebral disc degeneration

Immuno-Modulatory Effects of Intervertebral Disc Cells (opens in new window)

Author(s): Bermudez-Lekerika P, Crump KB, Tseranidou S, Nüesch A, Kanelis E, Alminnawi A, Baumgartner L, Muñoz-Moya E, Compte R, Gualdi F, Alexopoulos LG, Geris L, Wuertz-Kozak K, Le Maitre CL, Noailly J, Gantenbein B
Published in: Frontiers in Cell and Developmental Biology, Issue 10, 2022, ISSN 2296-634X
Publisher: frontiers
DOI: 10.3389/fcell.2022.924692

TNF induces catabolism in human cartilaginous endplate cells in 3D agarose culture under dynamic compression (opens in new window)

Author(s): Katherine B. Crump, Exarchos Kanelis, Maria Segarra-Queralt, Andreu Pascuet-Fontanet, Paola Bermudez-Lekerika, Ahmad Alminnawi, Liesbet Geris, Leonidas G. Alexopoulos, Jérôme Noailly, Benjamin Gantenbein
Published in: Scientific Reports, Issue 15, 2025, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-025-00538-w

Sulfated Hydrogels in Intervertebral Disc and Cartilage Research (opens in new window)

Author(s): Lazarus E, Bermudez-Lekerika P, Farchione D, Schofield T, Howard S, Mambetkadyrov I, Lamoca M, Rivero IV, Gantenbein B, Lewis CL, Wuertz-Kozak K
Published in: Cells, 2021, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells10123568

In-silico proteomic analysis of the role of IL-4 and IL-10 in IVD degeneration: Protein-protein interaction networks for candidate prioritisation (opens in new window)

Author(s): Paola Bermudez-Lekerika, Francesco Gualdi, Christine L. Le Maitre, Janet Piñero, Baldomero Oliva, Benjamin Gantenbein
Published in: Computational and Structural Biotechnology Journal, Issue 27, 2025, Page(s) 1600-1613, ISSN 2001-0370
Publisher: Elsevier BV
DOI: 10.1016/j.csbj.2025.04.015

Inhibition of the extracellular signal-regulated kinase pathway reduces the inflammatory component in nucleus pulposus cells (opens in new window)

Author(s): Tekari A, Marazza A, Crump K, Bermudez-Lekerika P, Gantenbein B
Published in: J Orthop Res, 2022, ISSN 1554-527X
Publisher: Wiley
DOI: 10.1002/jor.25273

Ex Vivo and In Vitro Proteomic Approach to Elucidate the Relevance of IL-4 and IL-10 in Intervertebral Disc Pathophysiology (opens in new window)

Author(s): Bermudez-Lekerika P, Tseranidou S, Kanelis E, Nüesch A, Crump KB, Alexopoulos LG, Wuertz-Kozak K, Noailly J, Le Maitre CL, Gantenbein B
Published in: JOR Spine, Issue 8(1), 2025, Page(s) e70048, ISSN 2572-1143
Publisher: Wiley & sons
DOI: 10.1002/jsp2.70048

EGR2, IGF1 and IL6 Expression Are Elevated in the Intervertebral Disc of Patients Suffering from Diffuse Idiopathic Skeletal Hyperostosis (DISH) Compared to Degenerative or Trauma Discs (opens in new window)

Author(s): Benjamin Gantenbein; Rahel Deborah May; Paola Bermudez-Lekerika; Katharina A. C. Oswald; Lorin Michael Benneker; Christoph E. Albers
Published in: Applied Sciences, Issue 2, 2021, Page(s) 4072, ISSN 2076-3417
Publisher: MDPI
DOI: 10.48350/156197

The Bone Morphogenetic Protein 2 Analogue L51P Enhances Spinal Fusion in Combination with BMP2 in an In Vivo Rat Tail Model (opens in new window)

Author(s): Gantenbein B, Oswald KA, Erbach GF, Croft AS, Bermudez-Lekerika P, Strunz F, Bigdon SF, Albers CE
Published in: Acta Biomaterialia, 2024, ISSN 1742-7061
Publisher: Elsevier BV
DOI: 10.1016/j.actbio.2024.01.039

Cartilaginous endplates: A comprehensive review on a neglected structure in intervertebral disc research (opens in new window)

Author(s): Crump KB, Alminnawi A, Bermudez-Lekerika P, Compte R, Gualdi F, McSweeney T, Muñoz-Moya E, Nüesch A, Geris L, Dudli S, Karppinen J, Noailly J, Le Maitre C, Gantenbein B
Published in: JOR Spine, Issue [epub, 2023, Page(s) e1294, ISSN 2572-1143
Publisher: Wiley
DOI: 10.1002/jsp2.1294

New Frontiers towards Regeneration of the Intervertebral Disc: On Progenitor Cells, Growth Factors and Biomaterials (opens in new window)

Author(s): Gantenbein, Benjamin
Published in: Regeneration of the Intervertebral Disc, Applied sciences special issue, Issue 5, 2021, ISSN 2076-3417
Publisher: MDPI
DOI: 10.3390/app112411913

Society of Back Pain Research Travel Fellowship 2021, price €2180

Author(s): Terence McSweeney
Published in: 2022
Publisher: Terence McSweeney

VPHI BEST POSTER AWARD 2022 WON BY MARIE SKLODOWSKA-CURIE PHD FELLOW SOFIA TSERANIDOU

Author(s): Virtual Physiological Human Institute for Integrative Biomedical Research
Published in: 2022
Publisher: Virtual Physiological Human Institute for Integrative Biomedical Research

Suomalainen Selkätutkimusseura Ry (Finnish Spine Society) early career researcher abstract prize 2022, €1000

Author(s): Terence McSweeney
Published in: 2022
Publisher: @TerMcS (Twitter)

Editorial: Immunological imbalance: What is its role in intervertebral disc degeneration? (opens in new window)

Author(s): Gantenbein B, Sun Z, Liu Z, Samartzis D
Published in: Frontiers in Cell and Developmental Biology, Issue 11, 2023, Page(s) 2, ISSN 2296-634X
Publisher: frontiers
DOI: 10.3389/fcell.2023.1196377